![]() ![]() Revatio (sildenafil) is prescribed for adults with pulmonary arterial hypertension (PAH). The active ingredient in Viagra can treat other disorders. Sildenafil for Pulmonary Arterial Hypertension (PAH) Viagra does not automatically cause an erection rather, it assists a man with ED in obtaining and keeping an erection when sexually aroused or stimulated. Viagra, as a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), works to block certain naturally occurring enzymes in the body, causing blood vessels to relax and enhancing blood flow to the penis. However, the significance of this link is still unclear. A 2014 study published in JAMA Internal Medicine also points to a possible link between the use of sildenafil (the active ingredient in Viagra) and melanoma, the most dangerous form of skin cancer. Viagra has always been linked to some serious side effects affecting the eyes, ears, penis, heart and blood vessels. The drugs entered the market in December 2017. In 2016, the FDA approved the first-ever generic version of Viagra to be manufactured and distributed by Teva, a Pennsylvania-based pharmaceutical company. The Journal of Sexual Medicine published results from one study that showed that “one out of every four new ED patients is under 40 years old.” Men’s Health reported around the same time that during the last two or three decades, ED rates have gone up, especially among younger men. In 2014, Fox News reported that “over 30 million men suffer from erectile dysfunction,” and it is estimated that approximately 20 million Americans have taken Viagra. Pfizer saw an economical advantage with this new discovery and experienced immediate success with Viagra, accumulating about a billion dollars in sales in its first year alone. Our writers are members of professional associations, including American Medical Writers Association, American Bar Association, The Alliance of Professional Health Advocates and International Society for Medical Publication Professionals. The information on has been medically and legally reviewed by more than 30 expert contributors, including doctors, pharmacists, lawyers, patient advocates and other health care professionals. This means the high-quality information we provide comes from credible sources, such as peer-reviewed medical journals and expert interviews. is HONCode (Health On the Net Foundation) certified. Our team includes experienced medical writers, award-winning journalists, researchers and certified medical and legal experts. ![]() We’ve also connected thousands of people injured by drugs and medical devices with top-ranked national law firms to take action against negligent corporations. has provided reliable, trusted information about medications, medical devices and general health since 2008.
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